Prions are small proteinaceous infectious particles. They are non-living and lack DNA. Prion diseases are often called Spongiform encephalopathies because diseased brains often appear with large vacuoles. Prion diseases are usually rapidly progressive and are always fatal.
I highly recommend looking at this single page for more information about prions.
A free, full-text review on prions by Stanley Prusiner can be found here.
More about Creutzfieldt-Jacob disease here.
Go here for the CDC Prion Disease page.
Some info on Alzheimer disease here.
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